Wednesday, May 1, 2013

Embryonic Stem Cell Research and Designer Babies: Where Do We Draw the Line?


            Have you ever wished you looked different? Maybe you want a different eye color or your teeth are really crooked. Maybe when you were a kid you were teased about your freckles or when you fell off the tire swing your broken leg didn’t heal quite right. Perhaps you were born with a “disability” or “deformity” and always feel awkward about meeting new people. Maybe, like me, you learned to talk around a stammering older brother and though he grew out of it, you never have. Maybe there’s a quirk about you that you wish you could change. And maybe, just maybe, you’ve thought about your own children and wondered if they’ll have to deal with the same kind of stuff.
            Advances in genetic research have begun to open doors for couples who want to screen the embryos (fertilized eggs) they produce. Pre-implantation genetic diagnosis (or PGD), a technique developed to look for genetic diseases in embryos, can also be used to determine the sex of the embryo. As science continues to advance, people are looking forward to a time when hopeful parents can select more than their child’s sex—they could select the physical traits of the child.
            This is not yet a possibility, and there are serious ethical implications of the availability of such a procedure. Some on the “for” side of this issue argue that human life does not begin until the implantation of the embryo in the uterus. Others on the same side argue for the “14-day mark,” which is related to the early development of the embryo. Because monozygotic twinning can occur until the 15th day of the pregnancy, the embryo is not yet a human fetus.
This argument makes me pause. It makes sense to me. When I consider identical twins I know, it is clear to me that they are two different people. If their lives began at conception, wouldn’t they be two halves of one whole? Or which twin is the “copy” of the person before the splitting? No, identical twins are genetic clones, not halves of one whole. They are distinct people—each twin possesses all the faculties of any other human being.
The argument that centers on implantation for the beginning of life makes less sense to me because the embryo itself does not have new properties, just a new location. In the 14-day mark argument, the embryo matures until it can no longer split and form an entirely new human being because the cells are differentiated past that point.
To make the ethical hubbub a little clearer, I need to emphasize that this is not like ordering a Sonic burger. This is not selecting children from a menu of sex and physical traits. This is producing several embryos in a lab using the couples’ eggs and sperm and then sending out the ones that do not meet the criteria. For now, technology can only screen for genetic diseases and sex. The leftover embryos—which could survive if allowed to be born, but are the wrong sex or genetically damaged—are usually sent to labs for embryonic stem cell research. Once they arrive there, they are destroyed in the process of removing their stem cells.
In a new development, though, a recent press release from the Advanced Cell Technology Company claims that their researchers have found a way to harvest embryonic stem cells without destroying the embryo itself. Instead, they use what they call “single blast technology,” where they take one stem cell and use it to produce more stem cells. This is similar to the PGD procedure that I briefly mentioned earlier. In PGD, the DNA in that one cell is analyzed for genetic diseases, which is possible because geneticists know where to look on the chromosomes for the mutated gene.
            This new and less destructive possibility makes me stop and think again. If embryonic stem cell research is ethically objectionable because the embryos are destroyed in the process of harvesting the stem cells, then is it okay if the embryos would not be harmed? But still, what would happen to all the leftover embryos from in vitro clinics? Would scientists freeze them for later use? That would probably not be a viable option because there are already hundreds of thousands of embryos worldwide—where would we keep them all? Then again, they probably wouldn’t take up very much space, so maybe a bank of catalogued embryos would be a good human resource (literally). Then all we would need would be artificial wombs and the human race would be set. I mean, if aliens invade the planet, I know I would want a fallback, just in case.
            If the ethical concern of using human embryos for spare parts is avoided by the Advanced Cell Technology Company’s technology, then all that remains between me and a designer baby are twenty years of scientific advances and my own personal beliefs. Since I have no control over the pace of science, I can only consider my own reaction. The first question I ask is, “Is it ethical?” Well, if there is no destruction of the extra embryos then I would answer with I don’t believe it’s unethical. The next question I ask, though, is this: “Is it responsible?” Just because science can do something, does that mean it should? If this technology is advanced and can become available to the general public at an affordable price, should it be made available? Should scientists and doctors give the choice to those with the means of creating the child they dream of having?
It appeals to me, but no. I prefer to let God be in charge of the life-making while I focus on the homemaking. I am thankful for advances in medicine, but I do not feel that attempting to pick and choose the traits of my offspring is a responsible use of technology.
Besides, my husband is so good-looking, I’m bound to have beautiful babies.

From the Author:
Thank you for reading! For more information on PGD and the Advanced Cell Technology Company, check out the following links.